负责人介绍
中国帕金森病影像学联盟联盟负责人介绍
吴涛
医学博士,首都医科大学宣武医院教授,博士生导师。曾留学德国、美国。研究方向为利用功能影像技术进行帕金森病神经机制及生物标记物研究,承担多项国家级及国外基金会课题。其作为联盟主要成员曾获得北京市科学技术奖一等奖及中华医学科技奖二等奖。发表50余篇SCI文章,引用4000次,H指数30,其中2篇进入帕金森病功能影像学研究领域引用前5名。其担任多个SCI期刊的编委和审稿人,并担任国家自然科学基金会、美国自然科学基金会(NSF)、美国The Michael J. Fox帕金森病基金会、英国帕金森基金会(Parkinson’s UK)、加拿大国家科学和工程研究会、法国国家研究局(ANR)、比利时国家自然科学基金委(FNRS)、比利时帕金森病基金会(BPF)等多个国内外基金会评审专家。
发表论文:
[1] Badea L, Onu M, Wu T, Roceanu A, Bajenaru O. Correction: Exploring the reproducibility of functional connectivity alterations in Parkinson's disease. PLOS ONE. 2018;13:e197121.
[2] Jia Q, Gao L, Zhang J, Wu T, Chan P. Altered functional connectivity of the subthalamic nucleus during self-initiated movement in Parkinson's disease. J Neuroradiol. 2018;45:249-55.
[3] Mi TM, Mei SS, Liang PP, Gao LL, Li KC, Wu T, et al. Author Correction: Altered resting-state brain activity in Parkinson's disease patients with freezing of gait. Sci Rep. 2018;8:4792.
[4] Wang J, Zhang JR, Zang YF, Wu T. Consistent decreased activity in the putamen in Parkinson's disease: a meta-analysis and an independent validation of resting-state fMRI. GIGASCIENCE. 2018;7:.
[5] Badea L, Onu M, Wu T, Roceanu A, Bajenaru O. Exploring the reproducibility of functional connectivity alterations in Parkinson's disease. PLOS ONE. 2017;12:e188196.
[6] Gao LL, Zhang JR, Chan P, Wu T. Levodopa Effect on Basal Ganglia Motor Circuit in Parkinson's Disease. CNS NEUROSCI THER. 2017;23:76-86.
[7] Gao L, Zhang J, Hou Y, Hallett M, Chan P, Wu T. The cerebellum in dual-task performance in Parkinson's disease. Sci Rep. 2017;7:45662.
[8] Mi TM, Mei SS, Liang PP, Gao LL, Li KC, Wu T, et al. Altered resting-state brain activity in Parkinson's disease patients with freezing of gait. Sci Rep. 2017;7:16711.
[9] Zeng LL, Xie L, Shen H, Luo Z, Fang P, Hou Y, Wu T, et al. Differentiating Patients with Parkinson's Disease from Normal Controls Using Gray Matter in the Cerebellum. CEREBELLUM. 2017;16:151-7.
[10] Gao LL, Wu T. The study of brain functional connectivity in Parkinson's disease. Transl Neurodegener. 2016;5:18.
[11] Wang Z, Chen H, Ma H, Ma L, Wu T, Feng T. Resting-state functional connectivity of subthalamic nucleus in different Parkinson's disease phenotypes. J NEUROL SCI. 2016;371:137-47.
[12] Wu T, Zhang J, Hallett M, Feng T, Hou Y, Chan P. Neural correlates underlying micrographia in Parkinson's disease. BRAIN. 2016;139:144-60.
[13] Zhang JR, Feng T, Hou YN, Chan P, Wu T. Functional Connectivity of Vim Nucleus in Tremor- and Akinetic-/Rigid-Dominant Parkinson's Disease. CNS NEUROSCI THER. 2016;22:378-86.
[14] Chen HM, Wang ZJ, Fang JP, Gao LY, Ma LY, Wu T, et al. Different patterns of spontaneous brain activity between tremor-dominant and postural instability/gait difficulty subtypes of Parkinson's disease: a resting-state fMRI study. CNS NEUROSCI THER. 2015;21:855-66.
[15] Hou Y, Zhang J, Chen B, Wu T. [Local brain activity in different motor subtypes of Parkinson's disease with fMRI]. Zhonghua Yi Xue Za Zhi. 2015;95:483-8.
[16] Ma H, Chen H, Fang J, Gao L, Ma L, Wu T, et al. Resting-state functional connectivity of dentate nucleus is associated with tremor in Parkinson's disease. J NEUROL. 2015;262:2247-56.
[17] Wu T, Hallett M, Chan P. Motor automaticity in Parkinson's disease. NEUROBIOL DIS. 2015;82:226-34.
[18] Wu T, Hou Y, Hallett M, Zhang J, Chan P. Lateralization of brain activity pattern during unilateral movement in Parkinson's disease. HUM BRAIN MAPP. 2015;36:1878-91.
[19] Wu T, Liu J, Zhang H, Hallett M, Zheng Z, Chan P. Attention to Automatic Movements in Parkinson's Disease: Modified Automatic Mode in the Striatum. CEREB CORTEX. 2015;25:3330-42.
[20] Wu T, Ma Y, Zheng Z, Peng S, Wu X, Eidelberg D, et al. Parkinson's disease-related spatial covariance pattern identified with resting-state functional MRI. J Cereb Blood Flow Metab. 2015;35:1764-70.
[21] Hou Y, Wu X, Hallett M, Chan P, Wu T. Frequency-dependent neural activity in Parkinson's disease. HUM BRAIN MAPP. 2014;35:5815-33.
[22] Wu T, Hallett M. The cerebellum in Parkinson's disease. BRAIN. 2013;136:696-709.
[23] Wu T, Wang J, Wang C, Hallett M, Zang Y, Wu X, et al. Basal ganglia circuits changes in Parkinson's disease patients. NEUROSCI LETT. 2012;524:55-9.
[24] Wu T, Long X, Wang L, Hallett M, Zang Y, Li K, et al. Functional connectivity of cortical motor areas in the resting state in Parkinson's disease. HUM BRAIN MAPP. 2011;32:1443-57.
[25] Wu T, Wang L, Hallett M, Chen Y, Li K, Chan P. Effective connectivity of brain networks during self-initiated movement in Parkinson's disease. NEUROIMAGE. 2011;55:204-15.
[26] Wu X, Yu C, Fan F, Zhang K, Zhu C, Wu T, et al. Correlation between progressive changes in piriform cortex and olfactory performance in early Parkinson's disease. EUR NEUROL. 2011;66:98-105.
[27] Fernagut PO, Li Q, Dovero S, Chan P, Wu T, Ravenscroft P, et al. Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. PLOS ONE. 2010;5:e14053.
[28] Wu T, Chan P, Hallett M. Effective connectivity of neural networks in automatic movements in Parkinson's disease. NEUROIMAGE. 2010;49:2581-7.
[29] Wu T, Wang L, Hallett M, Li K, Chan P. Neural correlates of bimanual anti-phase and in-phase movements in Parkinson's disease. BRAIN. 2010;133:2394-409.
[30] Wu T, Long X, Zang Y, Wang L, Hallett M, Li K, et al. Regional homogeneity changes in patients with Parkinson's disease. HUM BRAIN MAPP. 2009;30:1502-10.
[31] Wu T, Wang L, Chen Y, Zhao C, Li K, Chan P. Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. NEUROSCI LETT. 2009;460:6-10.
[32] Yang JF, Wu T, Li JY, Li YJ, Zhang YL, Chan P. DYT1 mutations in early onset primary torsion dystonia and Parkinson disease patients in Chinese populations. NEUROSCI LETT. 2009;450:117-21.
[33] Scheller D, Chan P, Li Q, Wu T, Zhang R, Guan L, et al. Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease. EXP NEUROL. 2007;203:415-22.
[34] Wu T, Hallett M. A functional MRI study of automatic movements in patients with Parkinson's disease. BRAIN. 2005;128:2250-9.